Across TCGA patient cohorts, PRB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,882 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRB3-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Stress granule assembly, and Regulation of nucleotide-excision repair. Each is linked with PRB3 in more than 17 cancer types. Because this analysis shows association rather than direction, both PRB3-to-partner and partner-to-PRB3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRB3→partner) and Y-score (partner→PRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.085	+0.233	.001	<.001	3	18
DLBC	Stress granule assembly →	+0.107	+0.252	<.001	<.001	3	17
KIRP	Regulation of nucleotide-excision repair →	+0.050	+0.147	<.001	<.001	3	16
DLBC	Regulation of mRNA catabolic process →	+0.059	+0.205	.008	.001	1	18
ESCA	Obsolete positive regulation of histone methylation →	+0.065	+0.465	<.001	<.001	3	16
ESCA	Protein localization to nucleoplasm →	+0.052	+0.397	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,882 associations by consensus.

Exploration

PRB3 survival (RNA) · tumor vs normal (RNA) · all PRB3 data types