Across TCGA cell cohorts, PRB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,453 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PRB3-associated GO terms across cancer lineages are Response to indole-3-methanol, Regulation of alternative mRNA splicing, via spliceosome, and Regulation of RNA splicing. Each is linked with PRB3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRB3-to-partner and partner-to-PRB3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRB3→partner) and Y-score (partner→PRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to indole-3-methanol →	+0.179	+0.260	.005	.004	3	8
OESOPHAGUS	Regulation of alternative mRNA splicing, via spliceosome →	+0.099	+0.383	.007	.006	2	8
LUNG_SCLC	Regulation of RNA splicing →	+0.064	+0.570	.005	.007	2	8
LUNG_SCLC	Regulation of mRNA splicing, via spliceosome →	+0.070	+0.525	.002	.005	3	7
LUNG_SCLC	Regulation of mRNA processing →	+0.071	+0.630	.004	.004	3	7
STOMACH	Protein localization to cytoplasmic stress granule →	+0.134	+0.256	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,453 associations by consensus.

Exploration

PRB3 survival (RNA) · tumor vs normal (RNA) · all PRB3 data types