PRANCR

Across TCGA pan-cancer cohorts, PRANCR RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of PRANCR’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where PRANCR RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PRANCR is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

BLCA, KICH, and LIHC are the cancer types where PRANCR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRANCR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.949	<.001	12	view →
KICH	Female	All	−1.151	<.001	8	view →
LIHC	Male	II,III,IV	+0.674	<.001	8	view →
HNSC	All	III,IV	+0.468	.007	7	view →
KIRC	All	III,IV	+0.318	.011	7	view →
THCA	Male	III,IV	−0.830	<.001	6	view →
LUSC	All	All	+0.336	.001	5	view →
STAD	All	All	+0.449	.004	4	view →
COAD	Female	II,III,IV	+0.419	.010	4	view →
LUAD	All	All	+0.338	.003	4	view →
CHOL	All	All	+1.592	<.001	3	view →
ESCA	All	All	+0.596	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

PRANCR–BLCA

Open the BLCA breakdown →