PRAMEF9

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRAMEF9 RNA expression is significantly associated with the mutation status of many other genes, with 222 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PRAMEF9-associated genes across cancer lineages are CNOT6L, CEP250, and TANC1. Each is linked with PRAMEF9 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF9-to-partner and partner-to-PRAMEF9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF9→partner) and Y-score (partner→PRAMEF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTCNOT6L →+5.357+0.263.003<.00133
LUNG_NSCLC_LUADCEP250 →+3.228+0.005.003.00233
URINARY_TRACTTANC1 →+4.087+0.010.009<.00132
URINARY_TRACTTRPM6 →+4.087+0.010.009<.00132
URINARY_TRACTSBNO1 →+5.087+0.013.004<.00132
PANCREASABCC11 →+4.614+0.005.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

Exploration