PRAMEF5

Across TCGA patient cohorts, PRAMEF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,127 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF5-associated GO terms across cancer lineages are Mitochondrial gene expression, Positive regulation of post-translational protein modification, and Spindle organization. Each is linked with PRAMEF5 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRAMEF5-to-partner and partner-to-PRAMEF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by PRAMEF5-low versus PRAMEF5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF5→partner) and Y-score (partner→PRAMEF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.165	+0.023	<.001	<.001	3	8
STAD	Positive regulation of post-translational protein modification →	+0.140	+0.022	<.001	<.001	3	8
STAD	Spindle organization →	+0.146	+0.022	<.001	<.001	3	8
STAD	RNA 5'-end processing →	+0.137	+0.021	<.001	<.001	3	8
STAD	Nucleoside phosphate biosynthetic process →	+0.139	+0.021	<.001	<.001	3	8
STAD	Protein targeting to mitochondrion →	+0.144	+0.020	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,127 associations by consensus.

Mitochondrial gene expression by PRAMEF5 expression — STAD

Explore this box plot interactively →