PRAMEF4

Across TCGA patient cohorts, PRAMEF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,515 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF4-associated GO terms across cancer lineages are Cellular respiration, Positive regulation of mitotic cell cycle, and Signal peptide processing. Each is linked with PRAMEF4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRAMEF4-to-partner and partner-to-PRAMEF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by PRAMEF4-low versus PRAMEF4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF4→partner) and Y-score (partner→PRAMEF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular respiration →	+0.120	+0.042	<.001	<.001	3	8
STAD	Positive regulation of mitotic cell cycle →	+0.088	+0.034	<.001	<.001	3	8
STAD	Signal peptide processing →	+0.086	+0.030	<.001	<.001	3	8
STAD	Protein folding →	+0.106	+0.033	<.001	<.001	3	7
STAD	NADH dehydrogenase complex assembly →	+0.117	+0.038	<.001	<.001	3	7
STAD	Cytochrome complex assembly →	+0.107	+0.031	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,515 associations by consensus.

Cellular respiration by PRAMEF4 expression — STAD

Explore this box plot interactively →