Across TCGA pan-cancer cohorts, PRAMEF30P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PRAMEF30P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where PRAMEF30P RNA is repressed in tumor relative to normal tissue. In most cancer types PRAMEF30P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where PRAMEF30P tumor–normal differential expression is most reproducible.