PRAMEF28P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PRAMEF28P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated PRAMEF28P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PRAMEF28P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRAMEF28P expression acts as an unfavorable survival marker.

STAD, BRCA, and LUAD are the cancer types where PRAMEF28P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileAll0.3880.671<.00181view →
BRCAOSTertileII,III,IV0.1360.567.00442view →
LUADOSTertileIII,IV0.2280.677.01536view →
CESCOSTertileIV0.0910.593<.00136view →
PCPGOSTertileAll0.5240.975<.00136view →
GBMOSTertileAll0.1170.435<.00118view →
UCECOSTertileIV0.2310.592.03618view →
LGGDFSTertileAll0.6780.834.0219view →
BLCAOSTertileIII,IV0.1730.579.0389view →
KIRPOSTertileAll0.2500.711.0079view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

PRAMEF28P–STAD (DFS)

Kaplan–Meier survival curve for PRAMEF28P RNA-high vs -low samples in STAD.

Open the STAD breakdown →

Exploration