PRAMEF27

Across TCGA cell cohorts, PRAMEF27 RNA expression is significantly associated with the mutation status of many other genes, with 85 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PRAMEF27-associated genes across cancer lineages are USPL1, UBAP2L, and ADAMTS19. Each is linked with PRAMEF27 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAMEF27-to-partner and partner-to-PRAMEF27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USPL1 grouped by PRAMEF27-low versus PRAMEF27-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF27→partner) and Y-score (partner→PRAMEF27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	USPL1 →	+4.384	+0.015	.006	<.001	3	2
BLOOD_Leukemia	UBAP2L →	+4.969	+0.019	.003	<.001	3	2
CNS	ADAMTS19 →	+3.459	+0.158	.006	<.001	3	2
LARGE_INTESTINE	PUS7L →	+4.022	+0.003	.006	<.001	3	2
LUNG_SCLC	WBP11 →	+4.643	+0.015	.004	<.001	3	1
LUNG_SCLC	ATRN →	+4.643	+0.015	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

USPL1 by PRAMEF27 expression — BLOOD_Leukemia

Explore this box plot interactively →