PRAMEF26

Across TCGA patient cohorts, PRAMEF26 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,348 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF26-associated GO terms across cancer lineages are rRNA modification, Type I interferon production, and Cellular response to insulin stimulus. Each is linked with PRAMEF26 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRAMEF26-to-partner and partner-to-PRAMEF26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA modification grouped by PRAMEF26-low versus PRAMEF26-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF26→partner) and Y-score (partner→PRAMEF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	rRNA modification →	+0.114	+0.009	<.001	<.001	3	4
STAD	Type I interferon production →	+0.129	+0.009	<.001	<.001	3	4
STAD	Cellular response to insulin stimulus →	+0.110	+0.009	<.001	<.001	3	4
STAD	Response to X-ray →	+0.098	+0.008	<.001	<.001	3	3
STAD	Regulation of double-strand break repair via homologous recombination →	+0.115	+0.008	<.001	<.001	3	3
STAD	Regulation of lamellipodium assembly →	+0.093	+0.008	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,348 associations by consensus.

rRNA modification by PRAMEF26 expression — STAD

Explore this box plot interactively →