Across TCGA patient cohorts, PRAMEF20 mutation is significantly associated with the RNA expression of many other genes, with 3,438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF20-associated genes across cancer lineages are TIPIN, NUP37, and SMC2. Each is linked with PRAMEF20 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRAMEF20-to-partner and partner-to-PRAMEF20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF20→partner) and Y-score (partner→PRAMEF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIPIN →	+0.606	+2.721	<.001	<.001	3	4
UCEC	NUP37 →	+0.395	+2.526	.002	.001	3	4
UCEC	SMC2 →	+0.666	+1.737	<.001	.002	3	4
UCEC	ZNHIT3 →	+0.477	+3.191	<.001	<.001	3	3
UCEC	TAF9 →	+0.654	+3.169	<.001	<.001	3	3
UCEC	FAM177A1 →	+0.417	+2.010	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

Exploration

PRAMEF20 survival (RNA) · tumor vs normal (RNA) · all PRAMEF20 data types