Across TCGA patient cohorts, PRAMEF20 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF20-associated genes across cancer lineages are TFRC, HER3_pY1289, and Notch1. Each is linked with PRAMEF20 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF20-to-partner and partner-to-PRAMEF20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF20→partner) and Y-score (partner→PRAMEF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.523	+2.115	.005	.017	3	3
UCEC	HER3_pY1289 →	+0.075	+1.827	.013	.015	3	2
UCEC	Notch1 →	+0.190	+2.820	<.001	.001	3	2
UCEC	RAD51 →	+0.119	+2.459	.015	.019	3	2
UCEC	Annexin-1 →	+0.367	+1.894	.049	.030	3	2
UCEC	CDK1 →	+0.134	+2.013	.012	.016	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

PRAMEF20 survival (RNA) · tumor vs normal (RNA) · all PRAMEF20 data types