PRAMEF2

Across TCGA patient cohorts, PRAMEF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,140 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF2-associated GO terms across cancer lineages are Cellular response to gamma radiation, Mitochondrial membrane organization, and Protein insertion into membrane. Each is linked with PRAMEF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRAMEF2-to-partner and partner-to-PRAMEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to gamma radiation grouped by PRAMEF2-low versus PRAMEF2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF2→partner) and Y-score (partner→PRAMEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular response to gamma radiation →	+0.087	+0.036	<.001	<.001	3	8
STAD	Mitochondrial membrane organization →	+0.106	+0.040	<.001	<.001	3	8
STAD	Protein insertion into membrane →	+0.108	+0.048	<.001	<.001	3	7
STAD	Vesicle localization →	+0.084	+0.036	<.001	<.001	3	7
STAD	Protein localization to mitochondrion →	+0.100	+0.045	<.001	<.001	3	7
STAD	Nucleoside bisphosphate metabolic process →	+0.073	+0.049	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,140 associations by consensus.

Cellular response to gamma radiation by PRAMEF2 expression — STAD

Explore this box plot interactively →