Across TCGA patient cohorts, PRAMEF19 mutation is significantly associated with the RNA expression of many other genes, with 1,108 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF19-associated genes across cancer lineages are RNU2-15P, RPS17P8, and RNU6-254P. Each is linked with PRAMEF19 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF19-to-partner and partner-to-PRAMEF19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF19→partner) and Y-score (partner→PRAMEF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU2-15P →	+0.413	+5.149	<.001	.007	3	3
LIHC	RPS17P8 →	+0.130	+5.268	<.001	.006	3	2
GBM	RNU6-254P →	+0.490	+4.969	<.001	.009	3	2
GBM	OR6C3 →	+0.113	+5.149	<.001	.007	3	2
BRCA	RN7SKP33 →	+0.119	+7.731	<.001	.009	3	2
HNSC	NME1P1 →	+0.175	+4.655	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,108 associations by consensus.

Exploration

PRAMEF19 survival (RNA) · tumor vs normal (RNA) · all PRAMEF19 data types