PRAMEF18

Across TCGA patient cohorts, PRAMEF18 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,626 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF18-associated GO terms across cancer lineages are Telomere maintenance in response to DNA damage, Obsolete mRNA polyadenylation, and Mitochondrial transport. Each is linked with PRAMEF18 in more than 10 cancer types. Because this analysis shows association rather than direction, both PRAMEF18-to-partner and partner-to-PRAMEF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance in response to DNA damage grouped by PRAMEF18-low versus PRAMEF18-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF18→partner) and Y-score (partner→PRAMEF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance in response to DNA damage →	+0.063	+0.185	<.001	<.001	3	11
STAD	Obsolete mRNA polyadenylation →	+0.073	+0.160	<.001	<.001	3	10
STAD	Mitochondrial transport →	+0.078	+0.175	<.001	<.001	3	10
STAD	Vacuolar transport →	+0.082	+0.167	<.001	<.001	3	10
STAD	Protein K48-linked deubiquitination →	+0.067	+0.176	<.001	<.001	3	10
STAD	Response to topologically incorrect protein →	+0.083	+0.172	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,626 associations by consensus.

Telomere maintenance in response to DNA damage by PRAMEF18 expression — STAD

Explore this box plot interactively →