PRAMEF18

Across TCGA cell cohorts, PRAMEF18 RNA expression is significantly associated with the mutation status of many other genes, with 121 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRAMEF18-associated genes across cancer lineages are CFB, TBC1D1, and ANKRD17. Each is linked with PRAMEF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAMEF18-to-partner and partner-to-PRAMEF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFB grouped by PRAMEF18-low versus PRAMEF18-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF18→partner) and Y-score (partner→PRAMEF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CFB →	+4.930	+0.026	.008	<.001	3	2
SKIN	TBC1D1 →	+4.415	+0.005	<.001	<.001	3	2
BLOOD_Lymphoma	ANKRD17 →	+3.643	+0.003	.001	<.001	3	2
BLOOD_Lymphoma	PAX9 →	+4.643	+0.004	.005	<.001	3	2
LUNG_NSCLC_LUAD	HEPHL1 →	+2.887	+0.003	.009	<.001	3	2
BLOOD_Myeloma	NCAM2 →	+4.807	+0.206	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

CFB by PRAMEF18 expression — SOFT_TISSUE

Explore this box plot interactively →