Across TCGA patient cohorts, PRAMEF17 mutation is significantly associated with the RNA expression of many other genes, with 1,741 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF17-associated genes across cancer lineages are SMIM35, SRSF10P1, and MTCO3P44. Each is linked with PRAMEF17 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF17-to-partner and partner-to-PRAMEF17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF17→partner) and Y-score (partner→PRAMEF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SMIM35 →	+0.126	+4.274	.003	.008	3	3
SKCM	SRSF10P1 →	+0.058	+1.439	.002	.004	3	3
LIHC	MTCO3P44 →	+0.092	+5.479	<.001	.002	3	2
READ	FABP5P4 →	+0.246	+5.925	<.001	.002	3	2
READ	RN7SL636P →	+0.145	+5.219	.001	.006	3	2
SKCM	LINC02096 →	+0.016	+1.934	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,741 associations by consensus.

Exploration

PRAMEF17 survival (RNA) · tumor vs normal (RNA) · all PRAMEF17 data types