PRAMEF17

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRAMEF17 RNA expression is significantly associated with the mutation status of many other genes, with 269 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PRAMEF17-associated genes across cancer lineages are TMPRSS7, MEP1B, and C15orf39. Each is linked with PRAMEF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAMEF17-to-partner and partner-to-PRAMEF17 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF17→partner) and Y-score (partner→PRAMEF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCTMPRSS7 →+4.643+0.010.004<.00132
LUNG_SCLCMEP1B →+4.643+0.010.004<.00132
LUNG_SCLCC15orf39 →+5.643+0.013.002<.00132
LUNG_SCLCOR51E2 →+4.643+0.010.004<.00132
LUNG_SCLCSRCIN1 →+4.058+0.008.007<.00132
BLOOD_LeukemiaADAM29 →+3.984+0.008.006<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 269 associations by consensus.

Exploration