Across TCGA patient cohorts, PRAMEF15 mutation is significantly associated with the RNA expression of many other genes, with 1,110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF15-associated genes across cancer lineages are GSTA6P, BMS1P14, and SNORD74B. Each is linked with PRAMEF15 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRAMEF15-to-partner and partner-to-PRAMEF15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF15→partner) and Y-score (partner→PRAMEF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GSTA6P →	+0.174	+3.401	.001	.006	3	4
BRCA	BMS1P14 →	+0.077	+4.760	<.001	.007	3	2
HNSC	SNORD74B →	+0.439	+5.578	<.001	.004	3	2
SKCM	UQCRHL →	+0.512	+3.534	<.001	.002	3	2
SKCM	EI24P4 →	+0.019	+2.291	.002	.006	3	2
COAD	SYPL1P1 →	+0.171	+5.693	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,110 associations by consensus.

Exploration

PRAMEF15 survival (RNA) · tumor vs normal (RNA) · all PRAMEF15 data types