Across TCGA patient cohorts, PRAMEF15 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF15-associated genes across cancer lineages are CD8+ T-cells, CD4+ T-cells, and Endothelial cells. Each is linked with PRAMEF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAMEF15-to-partner and partner-to-PRAMEF15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF15→partner) and Y-score (partner→PRAMEF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	CD8+ T-cells →	+0.058	+3.891	.013	.037	3	1
ESCA	CD4+ T-cells →	+0.025	+4.624	<.001	.014	3	1
UCEC	Endothelial cells →	-0.039	-3.148	.012	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.020	-3.138	.035	.019	3	1
UCEC	mv Endothelial cells →	-0.023	-1.796	.016	.028	3	1
UCEC	Basophils →	+0.153	+1.807	.028	.028	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

PRAMEF15 survival (RNA) · tumor vs normal (RNA) · all PRAMEF15 data types