PRAMEF15

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PRAMEF15 RNA expression is significantly associated with the mutation status of many other genes, with 204 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PRAMEF15-associated genes across cancer lineages are SETD1B, WIZ, and RELB. Each is linked with PRAMEF15 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF15-to-partner and partner-to-PRAMEF15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF15→partner) and Y-score (partner→PRAMEF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCSETD1B →+3.232+0.239.001.00633
UPPER_AERODIGESTIVE_TRACTWIZ →+4.357+0.157.006<.00133
SKINRELB →+4.196+0.065.002<.00132
LUNG_SCLCCNTN4 →+4.817+0.478.001<.00132
UPPER_AERODIGESTIVE_TRACTGUCY1A2 →+5.357+0.210.003<.00132
BLOOD_LeukemiaADAM29 →+3.984+0.008.006<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 204 associations by consensus.

Exploration