Across TCGA patient cohorts, PRAMEF14 mutation is significantly associated with the RNA expression of many other genes, with 2,143 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAMEF14-associated genes across cancer lineages are RNU6-1167P, CENPH, and CHAF1A. Each is linked with PRAMEF14 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF14-to-partner and partner-to-PRAMEF14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF14→partner) and Y-score (partner→PRAMEF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU6-1167P →	+0.682	+3.379	<.001	.003	3	3
UCEC	CENPH →	+0.763	+3.329	<.001	.005	3	3
UCEC	CHAF1A →	+0.584	+2.243	.003	.006	3	3
UCEC	FEN1 →	+0.731	+2.807	.001	.003	3	3
UCEC	SHCBP1 →	+0.719	+2.243	<.001	.006	3	3
UCEC	TIPIN →	+0.508	+2.928	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,143 associations by consensus.

Exploration

PRAMEF14 survival (RNA) · tumor vs normal (RNA) · all PRAMEF14 data types