PRAMEF13

Across TCGA patient cohorts, PRAMEF13 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,813 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PRAMEF13-associated GO terms across cancer lineages are ADP transport, Nucleosome organization, and Nucleobase biosynthetic process. Each is linked with PRAMEF13 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRAMEF13-to-partner and partner-to-PRAMEF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADP transport grouped by PRAMEF13-low versus PRAMEF13-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF13→partner) and Y-score (partner→PRAMEF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	ADP transport →	+0.064	+0.090	<.001	<.001	3	3
THYM	Nucleosome organization →	+0.047	+0.017	<.001	.001	3	2
TGCT	Nucleobase biosynthetic process →	+0.059	+0.095	<.001	<.001	3	2
TGCT	Positive regulation of synaptic vesicle endocytosis →	-0.077	-0.128	<.001	<.001	3	2
THYM	Regulation of lens fiber cell differentiation →	+0.092	+0.016	.009	.002	3	2
THYM	Negative regulation of response to wounding →	+0.039	+0.018	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,813 associations by consensus.

ADP transport by PRAMEF13 expression — TGCT

Explore this box plot interactively →