PRAMEF12

Across TCGA patient cohorts, PRAMEF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,191 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF12-associated GO terms across cancer lineages are Pyridine-containing compound metabolic process, Regulation of translational initiation, and Establishment of protein localization to mitochondrial membrane. Each is linked with PRAMEF12 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRAMEF12-to-partner and partner-to-PRAMEF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyridine-containing compound metabolic process grouped by PRAMEF12-low versus PRAMEF12-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF12→partner) and Y-score (partner→PRAMEF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Pyridine-containing compound metabolic process →	+0.050	+0.044	<.001	<.001	3	9
STAD	Regulation of translational initiation →	+0.078	+0.061	<.001	<.001	3	8
STAD	Establishment of protein localization to mitochondrial membrane →	+0.088	+0.044	<.001	<.001	3	8
STAD	Aerobic respiration →	+0.091	+0.074	<.001	<.001	3	8
STAD	Regulation of protein targeting →	+0.069	+0.038	<.001	.001	3	8
STAD	Viral gene expression →	+0.082	+0.042	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,191 associations by consensus.

Pyridine-containing compound metabolic process by PRAMEF12 expression — STAD

Explore this box plot interactively →