Across TCGA patient cohorts, PRAMEF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,346 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF10-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Establishment of protein localization to mitochondrial membrane, and Regulation of generation of precursor metabolites and energy. Each is linked with PRAMEF10 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRAMEF10-to-partner and partner-to-PRAMEF10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF10→partner) and Y-score (partner→PRAMEF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribose phosphate biosynthetic process →	+0.107	+0.023	<.001	<.001	3	8
STAD	Establishment of protein localization to mitochondrial membrane →	+0.121	+0.029	<.001	<.001	3	7
STAD	Regulation of generation of precursor metabolites and energy →	+0.084	+0.025	<.001	<.001	3	7
STAD	Aerobic respiration →	+0.130	+0.027	<.001	<.001	3	7
STAD	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.075	+0.023	<.001	<.001	3	7
STAD	Monosaccharide biosynthetic process →	+0.081	+0.023	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,346 associations by consensus.

Exploration

PRAMEF10 survival (RNA) · tumor vs normal (RNA) · all PRAMEF10 data types