PRAMEF1

Across TCGA patient cohorts, PRAMEF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,651 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRAMEF1-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Glucose metabolic process, and Mitochondrial transport. Each is linked with PRAMEF1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRAMEF1-to-partner and partner-to-PRAMEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by PRAMEF1-low versus PRAMEF1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF1→partner) and Y-score (partner→PRAMEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.146	+0.030	<.001	<.001	3	8
STAD	Glucose metabolic process →	+0.111	+0.044	<.001	<.001	3	8
STAD	Mitochondrial transport →	+0.133	+0.052	<.001	.001	3	7
STAD	Aerobic respiration →	+0.161	+0.029	<.001	<.001	3	7
STAD	Cytochrome complex assembly →	+0.124	+0.047	<.001	<.001	2	7
STAD	Mitochondrial translation →	+0.153	+0.027	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,651 associations by consensus.

Mitochondrial respiratory chain complex assembly by PRAMEF1 expression — STAD

Explore this box plot interactively →