PRAG1

Across TCGA patient cohorts, PRAG1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,821 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRAG1-associated genes across cancer lineages are BMP4, MYO1E, and PPP1R3B. Each is linked with PRAG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRAG1-to-partner and partner-to-PRAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRAG1 versus BMP4 in COAD, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAG1→partner) and Y-score (partner→PRAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BMP4 →	+1.681	+0.362	<.001	.001	3	5
OV	MYO1E →	+0.611	+0.410	<.001	<.001	3	5
OV	PPP1R3B →	+1.004	+0.415	<.001	<.001	3	5
OV	ITGA1 →	+0.900	+0.418	<.001	<.001	3	5
OV	IRAG1 →	+1.121	+0.342	<.001	<.001	3	5
OV	CTIF →	+0.636	+0.320	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,821 associations by consensus.

PRAG1 vs BMP4 — COAD

Explore this scatter interactively →