PRAF2

Across TCGA patient cohorts, PRAF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,370 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRAF2-associated proteins across cancer lineages are PCOLCE, CTHRC1, and DENND2D. Each is linked with PRAF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRAF2-to-partner and partner-to-PRAF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRAF2 versus PCOLCE in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAF2→partner) and Y-score (partner→PRAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+0.677	+0.900	.001	.001	3	6
OV	CTHRC1 →	+0.927	+0.972	.002	.005	3	5
HNSC	DENND2D →	-0.314	-0.604	<.001	<.001	3	5
OV	MFAP2 →	+0.831	+0.878	<.001	.001	3	5
COAD	CEP170 →	+0.246	+0.506	.003	<.001	3	5
LSCC	FKBP10 →	+0.489	+0.407	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,370 associations by consensus.

PRAF2 vs PCOLCE — OV

Explore this scatter interactively →