PRAF2

Across TCGA patient cohorts, PRAF2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRAF2-associated genes across cancer lineages are Platelets, Th1 cells, and Melanocytes. Each is linked with PRAF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAF2-to-partner and partner-to-PRAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by PRAF2-low versus PRAF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAF2→partner) and Y-score (partner→PRAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Platelets →	+0.032	+2.470	<.001	.012	3	1
UCEC	Th1 cells →	+0.113	+3.000	.036	.037	2	1
UCEC	Melanocytes →	-0.013	-2.946	.035	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by PRAF2 expression — UCEC

Explore this box plot interactively →