PRAC2

Across TCGA cell cohorts, PRAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,815 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRAC2-associated GO terms across cancer lineages are Lipophagy, Protein-RNA complex organization, and Embryonic skeletal joint morphogenesis. Each is linked with PRAC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRAC2-to-partner and partner-to-PRAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipophagy grouped by PRAC2-low versus PRAC2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAC2→partner) and Y-score (partner→PRAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Lipophagy →	+0.112	+2.775	.001	<.001	3	5
BONE	Protein-RNA complex organization →	+0.085	+2.532	.001	.002	3	5
PANCREAS	Embryonic skeletal joint morphogenesis →	-0.130	-0.371	.008	.007	2	6
PANCREAS	Embryonic neurocranium morphogenesis →	-0.150	-0.334	<.001	.005	2	5
BLOOD_Leukemia	Embryonic skeletal joint development →	-0.164	-0.459	.003	<.001	3	4
BONE	Negative regulation of tubulin deacetylation →	+1.196	+2.833	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,815 associations by consensus.

Lipophagy by PRAC2 expression — BONE

Explore this box plot interactively →