PQBP1

Across TCGA patient cohorts, PQBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,627 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PQBP1-associated proteins across cancer lineages are GPKOW, NONO, and THOC1. Each is linked with PQBP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PQBP1-to-partner and partner-to-PQBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PQBP1 versus GPKOW in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PQBP1→partner) and Y-score (partner→PQBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPKOW →	+0.327	+0.597	<.001	.001	3	8
LSCC	NONO →	+0.230	+0.461	<.001	<.001	3	7
LSCC	THOC1 →	+0.319	+0.356	<.001	.001	3	6
GBM	HUWE1 →	+0.216	+0.292	<.001	<.001	3	6
BRCA	MORF4L2 →	+0.298	+0.440	.006	.005	2	6
LSCC	PHF6 →	+0.412	+0.374	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,627 associations by consensus.

PQBP1 vs GPKOW — OV

Explore this scatter interactively →