PQBP1

Across TCGA patient cohorts, PQBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,349 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PQBP1-associated genes across cancer lineages are LMOD1, SUV39H1, and NCAPD2. Each is linked with PQBP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PQBP1-to-partner and partner-to-PQBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PQBP1 versus LMOD1 in OV, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PQBP1→partner) and Y-score (partner→PQBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LMOD1 →	-1.058	-0.213	<.001	.002	3	6
HNSC	SUV39H1 →	+0.752	+0.263	<.001	<.001	3	6
HNSC	NCAPD2 →	+0.749	+0.210	<.001	<.001	3	6
UCEC	RAD51AP1 →	+0.836	+0.192	<.001	<.001	3	6
LSCC	RFC5 →	+0.570	+0.141	<.001	<.001	3	6
BRCA	CDCA3 →	+1.157	+0.322	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,349 associations by consensus.

PQBP1 vs LMOD1 — OV

Explore this scatter interactively →