PQBP1

Across TCGA cell cohorts, PQBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,952 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PQBP1-associated GO terms across cancer lineages are Nucleolar chromatin organization, Nucleolus organization, and Growth hormone secretion. Each is linked with PQBP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PQBP1-to-partner and partner-to-PQBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar chromatin organization grouped by PQBP1-low versus PQBP1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PQBP1→partner) and Y-score (partner→PQBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Nucleolar chromatin organization →	+0.070	+0.629	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Nucleolus organization →	+0.093	+0.836	.001	<.001	3	10
URINARY_TRACT	Growth hormone secretion →	+0.172	+1.165	<.001	<.001	3	10
BONE	Pericentric heterochromatin formation →	+0.187	+0.883	<.001	<.001	3	10
BONE	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.154	+1.022	<.001	<.001	3	9
URINARY_TRACT	Tubulin deacetylation →	+0.130	+0.969	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,952 associations by consensus.

Nucleolar chromatin organization by PQBP1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →