PPY

Across TCGA cell cohorts, PPY protein abundance is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPY-associated genes across cancer lineages are PANK3, PTGES2, and TLCD4. Each is linked with PPY in more than 1 cancer types. Because this analysis shows association rather than direction, both PPY-to-partner and partner-to-PPY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPY versus PANK3 in BLOOD_Leukemia, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPY→partner) and Y-score (partner→PPY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PANK3 →	+0.556	+0.922	.007	.002	3	2
BLOOD_Leukemia	PTGES2 →	-0.724	-0.924	.007	.002	3	2
BLOOD_Leukemia	TLCD4 →	+0.925	+0.908	.005	.002	3	2
BLOOD_Leukemia	EIF5A2 →	+1.755	+1.039	.002	<.001	3	2
BLOOD_Leukemia	DMXL1 →	+0.711	+1.043	.002	<.001	3	2
BLOOD_Leukemia	CCDC85B →	-1.699	-0.993	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

PPY vs PANK3 — BLOOD_Leukemia

Explore this scatter interactively →