PPY

Across TCGA cell cohorts, PPY protein abundance is significantly associated with the protein abundance of many other proteins, with 114 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPY-associated proteins across cancer lineages are TCOF1, PYCR3, and CPT2. Each is linked with PPY in more than 1 cancer types. Because this analysis shows association rather than direction, both PPY-to-partner and partner-to-PPY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPY versus TCOF1 in BLOOD_Leukemia, with a Pearson correlation of 0.58.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPY→partner) and Y-score (partner→PPY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCOF1 →	+0.421	+0.809	.002	.006	3	2
BLOOD_Leukemia	PYCR3 →	-1.099	-0.913	.005	<.001	3	2
BLOOD_Leukemia	CPT2 →	-0.957	-1.050	.003	<.001	3	2
BLOOD_Leukemia	FAM207A →	+0.645	+0.758	.003	.007	3	2
BLOOD_Leukemia	GRK2 →	-1.051	-0.693	<.001	.001	3	2
BLOOD_Lymphoma	CDC27 →	+0.687	+1.020	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 114 associations by consensus.

PPY vs TCOF1 — BLOOD_Leukemia

Explore this scatter interactively →