PPWD1

Across TCGA patient cohorts, PPWD1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPWD1-associated genes across cancer lineages are CENPH, CCNB1, and CWC27. Each is linked with PPWD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPWD1-to-partner and partner-to-PPWD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPWD1 versus CENPH in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPWD1→partner) and Y-score (partner→PPWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CENPH →	+0.866	+0.238	<.001	<.001	3	7
GBM	CCNB1 →	+1.061	+0.276	<.001	<.001	3	6
OV	CWC27 →	+0.704	+0.338	<.001	<.001	3	6
OV	CENPK →	+0.625	+0.234	.001	.004	3	6
HNSC	POC5 →	+0.480	+0.174	.005	<.001	3	6
HNSC	SREK1 →	+0.648	+0.324	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,550 associations by consensus.

PPWD1 vs CENPH — GBM

Explore this scatter interactively →