PPRC1

Across TCGA patient cohorts, PPRC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,229 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPRC1-associated proteins across cancer lineages are NOLC1, SMC3, and DDX21. Each is linked with PPRC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PPRC1-to-partner and partner-to-PPRC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPRC1 versus NOLC1 in LUAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPRC1→partner) and Y-score (partner→PPRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NOLC1 →	+0.452	+0.548	<.001	<.001	3	7
GBM	SMC3 →	+0.351	+0.339	<.001	.001	2	7
BRCA	DDX21 →	+0.512	+0.587	.003	<.001	3	6
LSCC	DDX50 →	+0.271	+0.521	<.001	<.001	3	6
PDAC	SNRPD3 →	+0.382	+0.364	.004	.002	3	5
GBM	TIAL1 →	+0.201	+0.288	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,229 associations by consensus.

PPRC1 vs NOLC1 — LUAD

Explore this scatter interactively →