PPRC1

Across TCGA patient cohorts, PPRC1 protein abundance is significantly associated with the protein abundance of many other proteins, with 886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPRC1-associated proteins across cancer lineages are PLEKHG3_S1046, ATAD2_S1139, and GBF1_S612. Each is linked with PPRC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPRC1-to-partner and partner-to-PPRC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPRC1 versus PLEKHG3_S1046 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPRC1→partner) and Y-score (partner→PPRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHG3_S1046 →	+1.776	+0.513	.007	.008	2	2
LSCC	ATAD2_S1139 →	+1.752	+0.552	.008	<.001	3	1
LSCC	GBF1_S612 →	-1.025	-0.499	.001	<.001	3	1
LSCC	GTF2A1 →	+0.397	+0.504	<.001	<.001	3	1
LSCC	GTF2A2 →	+0.667	+0.475	.001	<.001	3	1
LSCC	GTSE1_S555 →	+1.239	+0.533	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 886 associations by consensus.

PPRC1 vs PLEKHG3_S1046 — LSCC

Explore this scatter interactively →