PPRC1

Across TCGA cell cohorts, PPRC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,566 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPRC1-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Ribosomal small subunit biogenesis, and Telomere maintenance in response to DNA damage. Each is linked with PPRC1 in more than 17 cancer types. Because this analysis shows association rather than direction, both PPRC1-to-partner and partner-to-PPRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by PPRC1-low versus PPRC1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPRC1→partner) and Y-score (partner→PPRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Maturation of SSU-rRNA →	+0.143	+0.816	<.001	<.001	3	17
BONE	Ribosomal small subunit biogenesis →	+0.133	+1.016	.001	<.001	3	17
BONE	Telomere maintenance in response to DNA damage →	+0.123	+0.667	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA replication proofreading →	+0.185	+0.800	<.001	<.001	3	17
BONE	'de novo' IMP biosynthetic process →	+0.178	+1.070	<.001	<.001	3	17
LIVER	Regulation of sister chromatid cohesion →	+0.133	+0.737	.001	.006	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,566 associations by consensus.

Maturation of SSU-rRNA by PPRC1 expression — OESOPHAGUS

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