PPP6R3

Across TCGA patient cohorts, PPP6R3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,436 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP6R3-associated proteins across cancer lineages are ZMYM2, NUMA1, and NXF1. Each is linked with PPP6R3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP6R3-to-partner and partner-to-PPP6R3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP6R3 versus ZMYM2 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP6R3→partner) and Y-score (partner→PPP6R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZMYM2 →	+0.329	+0.273	<.001	<.001	3	6
BRCA	NUMA1 →	+0.418	+0.497	<.001	<.001	3	5
GBM	NXF1 →	+0.259	+0.248	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.362	+0.545	<.001	<.001	3	5
LSCC	CTR9 →	+0.203	+0.486	.004	.005	3	5
PDAC	ZNF318_S709 →	+0.612	+0.394	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,436 associations by consensus.

PPP6R3 vs ZMYM2 — GBM

Explore this scatter interactively →