PPP6R2

Across TCGA patient cohorts, PPP6R2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,735 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP6R2-associated genes across cancer lineages are RMI2, ALG3, and AUP1. Each is linked with PPP6R2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP6R2-to-partner and partner-to-PPP6R2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP6R2 versus RMI2 in BRCA, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP6R2→partner) and Y-score (partner→PPP6R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RMI2 →	-0.667	-0.191	<.001	<.001	3	6
LSCC	ALG3 →	-0.644	-0.138	.002	.005	3	6
LSCC	AUP1 →	-0.465	-0.225	<.001	<.001	3	5
UCEC	TROAP →	-0.854	-0.117	.001	.004	3	5
LSCC	PRR11 →	-0.818	-0.203	<.001	<.001	3	5
BRCA	XBP1 →	+1.610	+0.248	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,735 associations by consensus.

PPP6R2 vs RMI2 — BRCA

Explore this scatter interactively →