PPP6R1

Across TCGA patient cohorts, PPP6R1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,023 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PPP6R1-associated proteins across cancer lineages are SAMHD1_T592, STK4, and ITGAM. Each is linked with PPP6R1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP6R1-to-partner and partner-to-PPP6R1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP6R1 versus SAMHD1_T592 in CCRCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP6R1→partner) and Y-score (partner→PPP6R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SAMHD1_T592 →	+0.784	+0.344	<.001	<.001	3	4
OV	STK4 →	+0.308	+0.754	.007	.002	3	4
CCRCC	ITGAM →	+0.446	+0.267	.001	<.001	3	3
PDAC	NAPA →	+0.260	+0.313	.007	.002	3	3
COAD	PBLD →	-0.614	-0.627	<.001	<.001	3	3
LUAD	UBE2M →	+0.216	+0.373	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,023 associations by consensus.

PPP6R1 vs SAMHD1_T592 — CCRCC

Explore this scatter interactively →