PPP6C

Across TCGA cell cohorts, PPP6C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,711 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP6C-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Immunoglobulin heavy chain V-D-J recombination, and Protein autoubiquitination. Each is linked with PPP6C in more than 16 cancer types. Because this analysis shows association rather than direction, both PPP6C-to-partner and partner-to-PPP6C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by PPP6C-low versus PPP6C-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP6C→partner) and Y-score (partner→PPP6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Proteasome regulatory particle assembly →	+0.181	+0.791	<.001	<.001	3	17
PANCREAS	Immunoglobulin heavy chain V-D-J recombination →	+0.209	+0.633	<.001	<.001	3	16
OESOPHAGUS	Protein autoubiquitination →	+0.049	+0.788	.001	<.001	3	15
PANCREAS	Positive regulation of mRNA 3'-end processing →	+0.141	+0.665	<.001	<.001	3	14
LIVER	Positive regulation of chromosome condensation →	+0.234	+0.854	<.001	<.001	3	13
SOFT_TISSUE	V(D)J recombination →	+0.116	+0.639	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,711 associations by consensus.

Proteasome regulatory particle assembly by PPP6C expression — LIVER

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