PPP5D1

Across TCGA patient cohorts, PPP5D1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,878 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPP5D1-associated proteins across cancer lineages are PGAM1_S31, CASP4, and LARP4_S583. Each is linked with PPP5D1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP5D1-to-partner and partner-to-PPP5D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP5D1 versus PGAM1_S31 in HNSC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP5D1→partner) and Y-score (partner→PPP5D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PGAM1_S31 →	-0.757	-0.358	<.001	<.001	3	5
GBM	CASP4 →	-0.483	-0.348	<.001	<.001	3	5
LUAD	LARP4_S583 →	-0.451	-0.230	<.001	<.001	3	5
BRCA	CKAP4_S26 →	-0.848	-0.199	<.001	.008	3	5
BRCA	EIF5B_S1168 →	-0.554	-0.206	<.001	<.001	3	5
BRCA	ARHGAP35 →	+0.351	+0.253	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,878 associations by consensus.

PPP5D1 vs PGAM1_S31 — HNSC

Explore this scatter interactively →