Across TCGA patient cohorts, PPP4R3C RNA expression is significantly associated with the go_rna of many other GO terms, with 6,035 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP4R3C-associated GO terms across cancer lineages are DNA conformation change, Mitotic nuclear division, and Positive regulation of cell cycle checkpoint. Each is linked with PPP4R3C in more than 11 cancer types. Because this analysis shows association rather than direction, both PPP4R3C-to-partner and partner-to-PPP4R3C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R3C→partner) and Y-score (partner→PPP4R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA conformation change →	+0.067	+0.167	<.001	<.001	3	11
STAD	Mitotic nuclear division →	+0.095	+0.215	<.001	<.001	3	10
STAD	Positive regulation of cell cycle checkpoint →	+0.060	+0.145	<.001	<.001	3	10
STAD	Chaperone-mediated protein folding →	+0.067	+0.124	<.001	.001	3	10
STAD	DNA replication →	+0.092	+0.212	<.001	<.001	3	10
STAD	DNA-templated DNA replication →	+0.073	+0.136	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,035 associations by consensus.

Exploration

PPP4R3C survival (RNA) · tumor vs normal (RNA) · all PPP4R3C data types