PPP4R3C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PPP4R3C RNA expression is significantly associated with the go_rna of many other GO terms, with 159 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible PPP4R3C-associated GO terms across cancer lineages are Response to mitochondrial depolarisation, Spliceosomal tri-snRNP complex assembly, and Mannose metabolic process. Each is linked with PPP4R3C in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP4R3C-to-partner and partner-to-PPP4R3C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R3C→partner) and Y-score (partner→PPP4R3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaResponse to mitochondrial depolarisation →+0.089+1.247.001<.00133
BLOOD_MyelomaSpliceosomal tri-snRNP complex assembly →+0.079+1.230<.001<.00133
BLOOD_MyelomaMannose metabolic process →+0.096+1.248.004.00332
BLOOD_MyelomaTranslational initiation →+0.066+0.968.001.00523
BLOOD_MyelomaAmine biosynthetic process →-0.128-1.492.008<.00132
CNSRegulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →+0.061+0.376<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

Exploration