PPP4R3B

Across TCGA patient cohorts, PPP4R3B protein abundance is significantly associated with the RNA expression of many other genes, with 9,030 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP4R3B-associated genes across cancer lineages are PNO1, CDCA8, and ESPL1. Each is linked with PPP4R3B in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP4R3B-to-partner and partner-to-PPP4R3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP4R3B versus PNO1 in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R3B→partner) and Y-score (partner→PPP4R3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PNO1 →	+0.505	+0.283	<.001	<.001	3	5
UCEC	CDCA8 →	+1.295	+0.288	<.001	<.001	3	5
GBM	ESPL1 →	+0.902	+0.248	<.001	.001	3	5
GBM	BUB1B →	+1.129	+0.267	<.001	.001	3	5
UCEC	CDC25A →	+1.052	+0.259	<.001	<.001	3	5
GBM	CDCA2 →	+1.139	+0.301	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,030 associations by consensus.

PPP4R3B vs PNO1 — LSCC

Explore this scatter interactively →