PPP4R3B

Across TCGA cell cohorts, PPP4R3B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,627 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP4R3B-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, mRNA destabilization, and Regulation of hematopoietic stem cell differentiation. Each is linked with PPP4R3B in more than 15 cancer types. Because this analysis shows association rather than direction, both PPP4R3B-to-partner and partner-to-PPP4R3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by PPP4R3B-low versus PPP4R3B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R3B→partner) and Y-score (partner→PPP4R3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment of mitotic sister chromatid cohesion →	+0.120	+0.688	.006	.006	3	16
LUNG_NSCLC_LUSC	mRNA destabilization →	+0.092	+0.892	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of hematopoietic stem cell differentiation →	+0.123	+0.953	.002	<.001	3	14
SOFT_TISSUE	Positive regulation of mRNA metabolic process →	+0.061	+0.685	<.001	<.001	3	14
LUNG_SCLC	RNA destabilization →	+0.058	+0.372	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of microtubule cytoskeleton organization →	+0.077	+0.754	.003	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,627 associations by consensus.

Establishment of mitotic sister chromatid cohesion by PPP4R3B expression — URINARY_TRACT

Explore this box plot interactively →