PPP4C

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PPP4C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP4C-associated genes across cancer lineages are FAM205A. Each is linked with PPP4C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP4C-to-partner and partner-to-PPP4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by PPP4C-low versus PPP4C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4C→partner) and Y-score (partner→PPP4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFAM205A →+0.038+5.029<.001<.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

FAM205A by PPP4C expression — LARGE_INTESTINE

Box plot of FAM205A in PPP4C-low vs PPP4C-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration