Across TCGA patient cohorts, PPP3R1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,303 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP3R1-associated proteins across cancer lineages are SPAST, WRNIP1, and MPHOSPH10. Each is linked with PPP3R1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP3R1-to-partner and partner-to-PPP3R1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3R1→partner) and Y-score (partner→PPP3R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPAST →	+0.529	+0.525	<.001	<.001	3	6
HNSC	WRNIP1 →	+0.313	+0.692	<.001	<.001	3	5
LUAD	MPHOSPH10 →	+0.314	+0.338	<.001	<.001	3	5
LSCC	MSH2 →	+0.551	+0.488	<.001	<.001	3	5
LSCC	NUP188 →	+0.167	+0.426	<.001	<.001	3	5
LSCC	UTP4 →	+0.282	+0.440	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,303 associations by consensus.

Exploration

PPP3R1 survival (RNA) · tumor vs normal (RNA) · all PPP3R1 data types